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Objective
The intravenous formulation of lacosamide (LCM) and its good overall tolerability and safety favor the use in status epilepticus (SE). The aim of this systematic review was to identify and evaluate studies reporting on the use of LCM in SE.
Methods
We performed a systematic literature search of electronic databases using a combined search strategy from 2008 until October 2016. Using a...
Perforant pathway stimulation (PPS) is used to study temporal lobe epilepsy in rodents. High‐frequency PPS induces acute seizures, which can lead to neuron death and spontaneous epilepsy. However, the minimum duration of PPS that induces neurodegeneration in naive rodents is unknown. Freely moving Sprague‐Dawley rats received one episode of continuous, bilateral PPS (range 1–180 min). Simultaneous...
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