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J. Neurochem. (2011) 119, 364–376.
AbstractThe atypical antipsychotic, olanzapine (OLZ), is used to treat bipolar disorder, but its therapeutic mechanism of action is not clear. Arachidonic acid (AA, 20:4n‐6) plays a critical role in brain signaling and an up‐regulated AA metabolic cascade was reported in postmortem brains from bipolar disorder patients. In this study, we tested whether, similar...
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