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The goal of this study was to detect early changes in the cartilage matrix caused by immobilization in a rabbit model of immobilization-induced osteoarthritis (OA) by T2 mapping with 7.0T MRI.Left knee joints of 28 mature rabbits were immobilized at 180° of extension with orthopedic casting tape for 1, 2, or 3weeks (n=7 rabbits each). No immobilization was performed in the control group (n=7 rabbits)...
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