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Aims
To evaluate the prevalence of electrocardiogram (ECG) abnormalities in marijuana users as an indirect measure of subclinical cardiovascular disease (CVD).
Design
Longitudinal and cross‐sectional secondary data analysis from the CARDIA (Coronary Artery Risk Development in Young Adults) study.
Setting
Four communities in the United States.
Participants
A total of 2585 participants from the...
Background and aims
Unlike tobacco, the effect of marijuana smoke on subclinical atherosclerosis, a surrogate measure for cardiovascular disease, is not known. This study aimed to determine the association between lifetime exposure to marijuana and measures of subclinical atherosclerosis in mid‐life.
Design, setting and participants
We used data from the US‐based Coronary Artery Risk Development...
Background and aims
Methamphetamine use is increasingly prevalent and associated with HIV transmission. Early‐phase human studies suggested naltrexone reduced amphetamine use among dependent individuals. We tested if extended‐release naltrexone (XRNTX) reduces methamphetamine use and associated sexual risk behaviors among high‐risk methamphetamine‐dependent men who have sex with men (MSM).
Design...
AimsTo describe characteristics of participants and overdose reversals associated with a community‐based naloxone distribution program and identify predictors of obtaining naloxone refills and using naloxone for overdose reversal.
DesignBivariate statistical tests were used to compare characteristics of participants who obtained refills and reported overdose reversals versus those who did not. We...
AimsTo estimate physical activity trajectories for people who quit smoking, and compare them to what would have been expected had smoking continued.
Design, Setting and ParticipantsA total of 5115 participants in the Coronary Artery Risk Development in Young Adults Study (CARDIA) study, a population‐based study of African American and European American people recruited at age 18–30 years in 1985/6...
AimsTo test aripiprazole for efficacy in decreasing use in methamphetamine‐dependent adults, compared to placebo.
DesignParticipants were randomized to receive 12 weeks of aripiprazole or placebo, with a 3‐month follow‐up and a platform of weekly 30‐minute substance abuse counseling.
SettingThe trial was conducted from January 2009 to March 2012 at the San Francisco Department of Public Health....
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