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Objective
Limited evidence is available to guide treatment of depression for persons with epilepsy. We evaluated the comparative effectiveness of sertraline and cognitive behavior therapy (CBT) for depression, quality of life, seizures, and adverse treatment effects.
Methods
We randomly assigned 140 adult outpatients with epilepsy and current major depressive disorder to sertraline or weekly CBT...
ObjectiveWe developed a novel method to map behavioral effects of deep brain stimulation (DBS) across a 3‐dimensional brain region and to assign statistical significance after stringent type I error correction. This method was applied to behavioral changes in Parkinson disease (PD) induced by subthalamic nucleus (STN) DBS to determine whether these responses depended on anatomical location of DBS...
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