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Hintergrund Die Herzinsuffizienz ist die Endstrecke ätiopathogenetisch unterschiedlicher myokardialer Schädigungen und mit substanzieller Morbidität und Mortalität assoziiert. Regenerative Therapiekonzepte sind potenziell durch die Stammzelltherapie realisierbar. Fragestellung Zur definitiven myokardialen Regeneration ist eine Stammzelldifferenzierung in Kardiomyozyten nötig. Adulte Stammzellen...
Coronary artery revascularization on the beating heart without the use of cardiopulmonary bypass (CPB) involves a more technically challenging anastomosis. Stabilizers are a major tool in OPCAB procedures, reducing the cardiac surface motion during suturing of the anastomosis. Initial attempts with multiple stay sutures, vessel loops, slings, and pharmacological movement adaptation with adenosine...
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