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Functional lox-like sequences have been identified within the yeast and mammalian genome. These hetero-specific lox sites also allow Cre recombinase to specifically target efficient integration of exogenous DNA into the endogenous pseudo-lox (=lox) sequences that occur naturally in the host genome using a Cre/loxP integrative recombination system. We investigated whether the Cre/=lox system is useful...
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