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Abstract. Rationale: Daily, 3-h separations from the dam on postnatal days 214 produce long-lasting changes in behavioral and neuroendocrine responses to stressors and sensitivity to acute morphine in Long-Evans rats. Objective: We tested whether offspring that were separated from their dam for 3h daily (MS) on postnatal days 214 exhibit altered sensitivity to chronic morphine, compared to animals...
Abstract. Rationale: According to recent studies daily, 3-h separations from the dam on postnatal days214 produce long-lasting changes in responses to stressors and sensitivity to morphine in Long-Evans offspring. It has not been investigated whether daily damlitter separations can have long-lasting effects also on the mother beyond weaning of the pups. Objective: We tested whether dams that were...
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