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Purpose This study was conducted to identify the maximum-tolerated dose (MTD) of fixed-dose-rate gemcitabine (FDR-gem) administered concurrently with S-1 and radical radiation for locally advanced pancreatic cancer (LAPC) and to provide efficacy and safety data. Methods Patients with unrespectable pancreatic cancer confined to the pancreatic region were treated with FDR-gem (300–400 mg/m2, 5 mg/m...
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