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Background
Use of surveillance mammography and magnetic resonance imaging (MRI) has been understudied among women with variant of uncertain significance (VUS) compared to pathogenic and likely pathogenic variants (P/LP).
Methods
Using data from two cancer settings, we calculated use of risk‐reducing mastectomy (RRM) and surveillance during each 13‐month span after genetic testing up to 6 years...
Background
This study was conducted to identify clinicodemographic risk factors for xerostomia among long‐term oropharyngeal cancer (OPC) survivors.
Methods
This cross‐sectional study included 906 disease‐free, adult OPC survivors with a median survival duration at the time of survey of 6 years (range, 1‐16 years); self‐reported xerostomia scores were available for 877 participants. Study participants...
Background
Oral mucositis (OM) is a debilitating sequela for patients treated for squamous cell carcinoma of the head and neck (HNSCC). This study investigated whether oral microbial features before treatment or during treatment are associated with the time to onset of severe OM in patients with HNSCC.
Methods
This was a cohort study of newly diagnosed patients with locoregional HNSCC who received...
BACKGROUND:Effective management of symptoms in cancer patients requires early intervention. This study assessed whether the timing of referral to the Supportive Care Center (SCC) and symptom burden outcome varied by race or ethnicity in lung cancer patients who had been seen at a tertiary cancer center.
METHODS:Non‐Hispanic white (n = 752), Hispanic (n = 111), and non‐Hispanic black (n = 117) patients...
BACKGROUND:Growing evidence suggests that single nucleotide polymorphisms (SNPs) in nucleotide excision repair (NER) pathway genes play an important role in bladder cancer etiology. However, only a limited number of genes and variations in this pathway have been evaluated to date.
METHODS:In this study, the authors applied a comprehensive pathway‐based approach to assess the effects of 207 tagging...
BACKGROUND:Recent genome‐wide association studies of lung cancer have shown that the CHRNA5‐A3 region on chromosome 15q24‐25.1 is strongly associated with an increased risk of lung cancer and nicotine dependence, and is thought to be associated with chronic obstructive pulmonary disease as well. However, it has not been established whether the association between genetic variants and lung cancer risk...
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