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We report on a rather unknown feature of oligonucleotides, namely, their potent antioxidant activity. Previously, we showed that nucleotides are potent antioxidants in FeII/CuI/II–H2O2 systems. Here, we explored the potential of 2′-deoxyoligonucleotides as inhibitors of the FeII/CuI/II-induced ·OH formation from H2O2. The oligonucleotides [d(A)5,7,20; d(T)20; (2′-OMe-A)5] proved to be highly potent...
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