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Acidic fibroblast growth factor (aFGF), which is produced in ependymal cells in the brain, is released into CSF after food intake or IP injection of glucose, while ICV infusion of aFGF produces a dose-dependent suppression of food intake in rats. When tested by passive avoidance and Morris water maze tasks after IP glucose injection, affective and spatial memory was significantly enhanced in mice...
Using Wistar SPF/VAF male (350-450g) and Zucker obese (500-800g) rats, we investigated effects of leptin on the neuronal activity on the hypothalamus, the vagal hepatic afferent and sympathetic efferent from the both brown and white adipose tissues (BAT/WAT) under urethane anesthetized and brain-slice preparations. Low doses (1-10 pg) of leptin inhibited glucose-sensitive vagal hepatic afferent discharges,...
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