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Diabetes mellitus is the most common serious metabolic disorder and it is considered to be one of the five leading causes of death in the world. Hyperglycemia-mediated oxidative stress plays a crucial role in diabetic complications. Hence, this study was undertaken to evaluate the protective effect of esculetin on the plasma glucose, insulin levels, tissue antioxidant defense system and lipid peroxidative...
Type 2 diabetes mellitus (T2DM) being a worldwide challenge to public health. The aim of this study was to examine the effect of esculetin, a major compound present in the herbal plant of Matricaria chamomilla L., on the key enzymes of carbohydrate metabolism in streptozotocin (STZ) induced diabetic rats. At first, the rats were induced intraperitonial injection of STZ (40mg/kgbw) to attain diabetes...
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