Search results for: Xiao Huang

Items from 1 to 20 out of 473 results

article

Long‐Term High‐Temperature Oxidation of Al₁₀CoCrFeNi₃₀ High‐Entropy Alloy

Anne Bastin, Taylor Robertson, Xiao Huang, Richard Kearsey

Advanced Engineering Materials > 26 > 20 > n/a - n/a

The combined effects of high‐temperature and long‐term exposure to oxidation environment on an AlCoCrFeNi‐based high entropy alloy (HEA) are investigated. The alloy has a composition of Al₁₀Co₂₀Cr₂₀Fe₂₀Ni₃₀ (at%) and is oxidized in lab air at 1000 °C for 1000 h to emulate working conditions and long operation cycles of gas turbines. The microstructure and oxide formation of the HEA are characterized...

article

Anisotropic Superprotonic Conduction in a Layered Single‐Component Hydrogen‐Bonded Organic Framework with Multiple In‐Plane Open Channels

Zhiwei Wang, Lijuan Yang, Qian Chen, Peiyuan Liu, more

Advanced Materials > 36 > 40 > n/a - n/a

Hydrogen‐bonded organic frameworks (HOFs) are promising proton conductive materials because of their inherent and abundant hydrogen‐bonding sites. However, most superprotonic‐conductive HOFs are constructed from multiple components to enable favorable framework architectures and structural integrity. In this contribution, layered HOF‐TPB‐A₃ with a single component is synthesized and exfoliated. The...

article

Dual‐Responsive Nanoreactor Initiates In Situ Generation of Copper Complex for Paraptosis‐Mediated Tumor Chemo‐Immunotherapy

Mei‐Ting Niu, Qian‐Ru Li, Qian‐Xiao Huang, Lin‐Meng Liu, more

Advanced Functional Materials > 34 > 39 > n/a - n/a

Paraptosis is a non‐apoptotic and caspase‐independent programmed cell death that can trigger immunogenic cell death (ICD) in tumor cells, representing a potent tactic to overcome immune tolerance to apoptosis. Here, this study demonstrates the construction of a dual‐responsive nanoreactor (MCGDH) to achieve paraptosis‐mediated ICD for chemo‐immunotherapy. Specifically, by doping Cu²⁺ into glutathione...

article

Storable Polydopamine Nanoparticles Combined with Bacillus Calmette‐Guérin for Photothermal‐Immunotherapy of Colorectal Cancer

Ze‐Nan Zhuang, Yong‐Dan Qi, Qian‐Xiao Huang, Cheng Zhang, more

Advanced Functional Materials > 34 > 39 > n/a - n/a

Photothermal immunotherapy emerges as a promising strategy for treating tumors. However, the majority of current photothermal immunotherapy approaches do not yet show significant potential for clinical translation. In this study, lyophilized polydopamine (PDA) nanoparticles combined with Bacillus Calmette–Guérin (BCG) are investigated for photothermal immunotherapy against colorectal cancer. By simply...

article

Exploration of the Mechanisms of Bu‐Yang‐Huan‐Wu Decoction in the Treatment of Diabetic Peripheral Neuropathy by Integrating of Serum Pharmacochemistry and Network Pharmacology

Peng‐Fei Chen, Guang‐Xiao Huang, Wen‐Ting Gu, Guo‐Dong Zhuang, more

Chemistry & Biodiversity > 21 > 9 > n/a - n/a

Diabetic peripheral neuropathy (DPN) is a significant and frequent complication of diabetes. Bu‐Yang‐Huan‐Wu Decoction (BHD) is a classic traditional Chinese herbal prescription that is commonly used in modern clinical practice for the effective treatment of DPN, but the underlying mechanism is not yet clearly defined. The chemical constituents of BHD were characterized by UPLC‐Q‐Orbitrap HR MS/MS,...

article

Serum bile acid profiles are associated with heart failure with preserved ejection fraction in patients with metabolic dysfunction‐associated fatty liver disease: An exploratory study

Xiao‐Dong Zhou, Cui‐Fang Xu, Qin‐Fen Chen, Michael D. Shapiro, more

Diabetes, Obesity and Metabolism > 26 > 9 > 3684 - 3695

Aim To analyse the association between serum bile acid (BA) profile and heart failure (HF) with preserved ejection fraction (HFpEF) in patients with metabolic dysfunction‐associated fatty liver disease (MAFLD). Methods We enrolled 163 individuals with biopsy‐proven MAFLD undergoing transthoracic echocardiography for any indication. HFpEF was defined as left ventricular ejection fraction >50%...

article

Elucidating the Bioinspired Synthesis Process of Magnetosomes‐Like Fe₃O₄ Nanoparticles (Small 21/2024)

Yu Mao, Jizi Liu, Jianfei Sun, Yifan Zhao, more

Small > 20 > 21 > n/a - n/a

Magnetotactic Bacteria Bioinspired synthesis and biosynthesis are often complementary. The study and understanding of the biomineralization process of magnetosomes can provide important guidance to the chemical synthesis of magnetosomes‐like Fe₃O₄ nanoparticles. Meanwhile, the in‐depth investigations of bioinspired syntheses can in turn bring us closer to nature and reveal the mechanism of biomeralization...

article

Elucidating the Bioinspired Synthesis Process of Magnetosomes‐Like Fe₃O₄ Nanoparticles

Yu Mao, Jizi Liu, Jianfei Sun, Yifan Zhao, more

Small > 20 > 21 > n/a - n/a

Iron oxide nanoparticles are a kind of important biomedical nanomaterials. Although their industrial‐scale production can be realized by the conventional coprecipitation method, the controllability of their size and morphology remains a huge challenge. In this study, a kind of synthetic polypeptide Mms6‐28 which mimics the magnetosome protein Mms6 is used for the bioinspired synthesis of Fe₃O₄ nanoparticles...

article

Phase‐Pure α‐FAPbI₃ Perovskite Solar Cells via Activating Lead–Iodine Frameworks

Tingting Niu, Lingfeng Chao, Yingdong Xia, Kaiyu Wang, more

Advanced Materials > 36 > 13 > n/a - n/a

Narrow bandgap cubic formamidine perovskite (α‐FAPbI₃) is widely studied for its potential to achieve record‑breaking efficiency. However, its high preparation difficulty caused by lattice instability is criticized. A popular strategy for stabilizing the α‐FAPbI₃ lattice is to replace intrinsic FA⁺ or I⁻ with smaller ions of MA⁺, Cs⁺, Rb⁺, and Br⁻, whereas this generally leads to broadened optical...

article

Allelic variation of PmCBF03 contributes to the altitude and temperature adaptability in Japanese apricot (Prunus mume Sieb. et Zucc.)

Xiao Huang, Feng Gao, Pengyu Zhou, Chengdong Ma, more

Plant, Cell & Environment > 47 > 4 > 1379 - 1396

Japanese apricot is an important subtropical deciduous fruit tree in China, widely distributed in different altitude areas. How does it adapt to the different temperature environments in these areas? In this study, we identified a low‐temperature transcription factor PmCBF03 on chromosome 7 through adaptive analysis of populations at different altitudes, which has an early termination single nucleotide...

article

Association between plasma CTRPs with cognitive impairment and neurodegeneration of Alzheimer's disease

Xiao Huang, Jialing Zhao, Qinghua Wang, Tingqi Yan, more

CNS Neuroscience & Therapeutics > 30 > 2 > n/a - n/a

Aims Recent evidence indicated the biological basis of complement 1q (C1q)/tumor necrosis factor (TNF)‐related protein (CTRP) 3, 4, and 14 for affecting brain structure and cognitive function. Thus, we aimed to investigate the association between plasma CTRPs with Alzheimer's disease (AD). Methods A multicenter, cross‐sectional study recruited patients with AD (n = 137) and cognitively normal (CN)...

article

A PD‐L1‐targeting Regulator for Metabolic Reprogramming to Enhance Glutamine Inhibition‐Mediated Synergistic Antitumor Metabolic and Immune Therapy

Xiao‐Kang Jin, Shi‐Man Zhang, Jun‐Long Liang, Shun‐Kang Zhang, more

Advanced Materials > 36 > 6 > n/a - n/a

Inhibition of glutamine metabolism in tumor cells can cause metabolic compensation‐mediated glycolysis enhancement and PD‐L1 upregulation‐induced immune evasion, significantly limiting the therapeutic efficacy of glutamine inhibitors. Here, inspired by the specific binding of receptor and ligand, a PD‐L1‐targeting metabolism and immune regulator (PMIR) are constructed by decorating the glutaminase...

article

Effect of percutaneous endoscopic gastrostomy prior to oesophageal cancer surgery on postoperative wound complications in patients: A meta‐analysis

Xiao Huang, Chunyang Jia, Ying Zhu

International Wound Journal > 21 > 2 > n/a - n/a

It is still a matter of controversy whether percutaneous endoscopic gastrostomy(PEG) should be used prior to the operation for the purpose of feeding the patient with resectable oesophageal carcinoma (EC). Comparison was made between EC and preoperatively treated PEG and non‐preoperative PEG. An extensive literature review has been conducted to determine the results about PEG and No‐PEG trials. In...

article

Effects of WuZhi preparations on tacrolimus in pediatric and adult patients carrying the CYP3A51* allele of heart transplant during the early period after transplantation

Li Liu, Ying Zhou, Xiao Huang, Hefen Chen, more

Clinical Transplantation > 38 > 1 > n/a - n/a

Aim Wuzhi preparations (WZP) are commonly administrated with tacrolimus (TAC) in China to improve the liver function and increase the exposure of TAC. This study aims to investigate the effects of WZP on TAC in pediatric heart transplantation (HTx) patients carrying the CYP3A5*1 allele during the early period after transplantation and also make a comparison with these effects in adult recipients...

article

Tetra‐Coordinated W₂S₃ for Efficient Dual‐pH Hydrogen Production

Lingbin Xie, Longlu Wang, Xia Liu, Weiwei Zhao, more

Angewandte Chemie International Edition > 63 > 5 > n/a - n/a

Two‐dimensional (2D) transition‐metal dichalcogenides (TMDs) have emerged as promising catalysts for the hydrogen evolution reaction (HER) that play a crucial role in renewable energy technologies. Breaking the inherent structural paradigm limitations of 2D TMDs is the key to exploring their fascinating physical and chemical properties, which is expected to develop a revolutionary HER catalyst. Herein,...

article

Tetra‐Coordinated W₂S₃ for Efficient Dual‐pH Hydrogen Production

Lingbin Xie, Longlu Wang, Xia Liu, Weiwei Zhao, more

Angewandte Chemie > 136 > 5 > n/a - n/a

article

Interaction between mitochondrial homeostasis and barrier function in lipopolysaccharide‐induced endothelial cell injury

Weiwei Zhu, Xiaojing Liu, Liqing Luo, Xiao Huang, more

International Journal of Experimental Pathology > 104 > 6 > 272 - 282

This study aimed to investigate the effects of mitochondrial homeostasis on lipopolysaccharide (LPS)‐induced endothelial cell barrier function and the mechanisms that underlie these effects. Cells were treated with LPS or oligomycin (mitochondrial adenosine triphosphate synthase inhibitor) and the mitochondrial morphology, mitochondrial reactive oxygen species (mtROS), and mitochondrial membrane potential...

article

Four Pairs of Neuroprotective Aryldihydronaphthalene‐Type Lignanamide Enantiomers from the Herbs of Solanum lyratum

Si‐Hui Mi, Ye Chang, Xin Zhang, Jiao‐Yang Hou, more

Chemistry & Biodiversity > 20 > 9 > n/a - n/a

Four pairs of aryldihydronaphthalene‐type lignanamide enantiomers were isolated from Solanum lyratum (Solanaceae). The enantiomeric separation was accomplished by chiral‐phase HPLC, and five undescribed compounds were elucidated. Analysis by various spectroscopy and ECD calculations, the structures of undescribed compounds were illuminated. The neuroprotective effects of all compounds were evaluated...

article

Inhalable Capsular Polysaccharide‐Camouflaged Gallium‐Polyphenol Nanoparticles Enhance Lung Cancer Chemotherapy by Depleting Local Lung Microbiota

Zi‐Yi Han, Qi‐Wen Chen, Di‐Wei Zheng, Ke‐Wei Chen, more

Advanced Materials > 35 > 38 > n/a - n/a

Local lung microbiota is closely associated with lung tumorigenesis and therapeutic response. It is found that lung commensal microbes induce chemoresistance in lung cancer by directly inactivating therapeutic drugs via biotransformation. Accordingly, an inhalable microbial capsular polysaccharide (CP)‐camouflaged gallium‐polyphenol metal–organic network (MON) is designed to eliminate lung microbiota...

article

A Gas/phototheranostic Nanocomposite Integrates NIR‐II‐Peak Absorbing Aza‐BODIPY with Thermal‐Sensitive Nitric Oxide Donor for Atraumatic Osteosarcoma Therapy

Zhijie Fang, Jiaxin Zhang, Zhenxiong Shi, Lan Wang, more

Advanced Materials > 35 > 35 > n/a - n/a

Photothermal therapy (PTT) has received increasing interest in cancer therapeutics owing to its excellent efficacy and controllability. However, there are two major limitations in PTT applications, which are the tissue penetration depth of lasers within the absorption range of photothermal agents and the unavoidable tissue empyrosis induced by high‐energy lasers. Herein, a gas/phototheranostic nanocomposite...

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INFONA - science communication portal

Search results for: Xiao Huang

Long‐Term High‐Temperature Oxidation of Al₁₀CoCrFeNi₃₀ High‐Entropy Alloy

Anisotropic Superprotonic Conduction in a Layered Single‐Component Hydrogen‐Bonded Organic Framework with Multiple In‐Plane Open Channels

Dual‐Responsive Nanoreactor Initiates In Situ Generation of Copper Complex for Paraptosis‐Mediated Tumor Chemo‐Immunotherapy

Storable Polydopamine Nanoparticles Combined with Bacillus Calmette‐Guérin for Photothermal‐Immunotherapy of Colorectal Cancer

Exploration of the Mechanisms of Bu‐Yang‐Huan‐Wu Decoction in the Treatment of Diabetic Peripheral Neuropathy by Integrating of Serum Pharmacochemistry and Network Pharmacology

Serum bile acid profiles are associated with heart failure with preserved ejection fraction in patients with metabolic dysfunction‐associated fatty liver disease: An exploratory study

Elucidating the Bioinspired Synthesis Process of Magnetosomes‐Like Fe₃O₄ Nanoparticles (Small 21/2024)

Elucidating the Bioinspired Synthesis Process of Magnetosomes‐Like Fe₃O₄ Nanoparticles

Phase‐Pure α‐FAPbI₃ Perovskite Solar Cells via Activating Lead–Iodine Frameworks

Allelic variation of PmCBF03 contributes to the altitude and temperature adaptability in Japanese apricot (Prunus mume Sieb. et Zucc.)

Association between plasma CTRPs with cognitive impairment and neurodegeneration of Alzheimer's disease

A PD‐L1‐targeting Regulator for Metabolic Reprogramming to Enhance Glutamine Inhibition‐Mediated Synergistic Antitumor Metabolic and Immune Therapy

Effect of percutaneous endoscopic gastrostomy prior to oesophageal cancer surgery on postoperative wound complications in patients: A meta‐analysis

Effects of WuZhi preparations on tacrolimus in pediatric and adult patients carrying the CYP3A51* allele of heart transplant during the early period after transplantation

Tetra‐Coordinated W₂S₃ for Efficient Dual‐pH Hydrogen Production

Tetra‐Coordinated W₂S₃ for Efficient Dual‐pH Hydrogen Production

Interaction between mitochondrial homeostasis and barrier function in lipopolysaccharide‐induced endothelial cell injury

Four Pairs of Neuroprotective Aryldihydronaphthalene‐Type Lignanamide Enantiomers from the Herbs of Solanum lyratum

Inhalable Capsular Polysaccharide‐Camouflaged Gallium‐Polyphenol Nanoparticles Enhance Lung Cancer Chemotherapy by Depleting Local Lung Microbiota

A Gas/phototheranostic Nanocomposite Integrates NIR‐II‐Peak Absorbing Aza‐BODIPY with Thermal‐Sensitive Nitric Oxide Donor for Atraumatic Osteosarcoma Therapy

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