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We have shown that immobilization stress causes changes in the spectrum of the heart's cytosole creatine kinase isoenzymes. In myocardium adult immobilized rats, MM isoenzyme is decreased and MB and BB isoenzymes are increased compared to intact animals. The pattern of isoenzyme response in old and adult rats was different. Immobilization of old rat caused an increase of MM and a decrease of MB isoenzyme...
We compared the effects of immobilization stress on the properties of mitochondrial creatine kinase (CK) isoenzyme from the myocardium of adult and old rats. Here we show that the activity of CK in the myocardium of old rats is lower in comparison to that in the myocardium of adult ones. During stress, CK activity in the myocardium of old rats increases, whereas in the myocardium of adults it does...
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