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Trimebutine maleate is a prokinetic agent that acts directly on the smooth muscle of the GI tract. A bioequivalence (BE) study of 2 oral formulations of 100 mg trimebutine maleate (TMB) was carried out in 24 healthy male Korean volunteers according to a crossover–randomized design.Subjects were given a single dose of 2 100 mg tablets of each formulation. The test and reference formulations were Recutin™...
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