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A 61-year-old women had been treated with methotrexate (MTX) since May 1993 for rheumatoid arthritis. She developed a high fever on 1 July 1997 and was diagnosed as havingListeria monocytogenes sepsis and meningoencephalitis. The encephalitis progressed inexorably and she died on 12 July. Although MTX is used as a first-line disease modifying anti-rheumatic drug, listeriosis should be remembered as...
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