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In this paper, we present a novel circular close-loop ferrofluid driven microchip for rapid polymerase chain reaction (PCR). A small ferrofluid plug, containing sub-domain magnetic particles in a liquid carrier, is driven by an external magnet along the circular microchannel, which in turn propels the PCR mixture through three temperature zones. Using magnet as the actuator eliminates the need for...
In this preliminary experimental study, micro-scale particle image velocimetry (μPIV) was adopted for the first time to get the quantitative information of magnetic flows in a micro-channel. The μPIV consists of an inverted florescent microscope, a Q-switch Nd:YAG laser and a CCD camera. The florescent liquid with particles of 3μm diameter was blended homogeneously with the prepared magnetic fluid...
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