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Tamoxifen and gefitinib (IRESSA™) combination therapy was studied in patients with ovarian cancer refractory or resistant to platinum- and taxane-based therapy.In this phase II study, 56 patients with epithelial ovarian carcinoma or cancer of the fallopian tube or peritoneum received oral tamoxifen 40 mg/day and gefitinib 500 mg/day until progression or unacceptable toxicity.Seventeen patients (mean...
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