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Twelve patients with chronic critical limb ischemia in whom a spinal cord stimulation (SCS) system had been implanted for at least one year had increased microvascular flow and achieved healing of trophic acral lesions. After switching off the system, the clinical improvement persisted for 10 days and the neurohormonal pattern showed high plasma values of β-endorphin and Met-enkephalin, normal dynorphin...
After hyperventilation, systolic and diastolic blood pressure (BP) significantly decreased in 14 hypertensive patients (group 1), did not change in 9 (group 2) and increased in 8 (group 3). Basal BP, norepinephrine and dynorphin B levels were higher in group 1 than in groups 2 and 3. The decrease in BP after hyperventilation was associated with a decrease in plasma norepinephrine, Met-enkephalin and...
Plasma opioid peptides, norepinephrine, atrial natriuretic factor (ANF) and blood pressure (BP) were assessed in 24 chronic obstructive pulmonary disease patients with acute respiratory failure. Hypoxemic-hypercapnic patients had high BP, β-endorphin, Met-enkephalin and dynorphin B, whereas hypoxemic-normocapnic and hypoxemic-hypocapnic patients showed normal BP, high β-endorphin, and normal Met-enkephalin...
After hyperventilation, systolic blood pressure (SBP) significantly decreased in 10 subjects (group 1), did not change in eight (group 2) and increased in 15 (group 3). Diastolic blood pressure and heart rate increased in all groups. The decrease in SBP was associated with a decrease in plasma catecholamines and increase in β-endorphin, whereas the increase in SBP was accompanied by an increase in...
Fontana, F., P. Bernardi, E. Merlo Pich, S. Boschi, R. De Iasio and S. Spampinato. Endogenous opioid peptides and mental stress in congestive heart failure patients. Peptides 19(1) 21-26, 1998.-Two groups of patients with acute congestive heart failure (CHF), New York Heart Association class III, presenting elevated plasma values of β-endorphin, norepinephrine, atrial natriuretic factor (ANF) and...
Fontana, F., P. Bernardi, E. Merlo Pich, S. Boschi, R. De Iasio, S. Spampinato and G. Grossi. Opioid peptide modulation of circulatory and endocrine response to mental stress in humans. Peptides 18(2) 169–175, 1997.—Healthy subjects were classified according to their percent increase in systolic blood pressure (SBP) after mental arithmetic test (MAT) as low (ΔSBP 9.3–15.1%, n = 15) and high (ΔSBP...
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