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The results presented here are twofold. First, a heuristic algorithm is proposed which, through removing some unnecessary arcs from a digraph, tends to reduce it into an ad joint and thus simplifies the search for a Hamiltonian cycle. Second, a heuristic algorithm for DNA sequence assembly is proposed, which uses a graph model of the problem instance, and incorporates two independent procedures of...
In the paper, the problem of isothermic DNA sequencing by hybridization, without any errors in its input data, is presented and an exact polynomial-time algorithm solving the problem is described. The correctness of the algorithm is confirmed by an enumerative proof.
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