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Photooxidation is a method of tissue fixation in the construction of bioprostheses. This process leads to the tissue protein crosslinking under light and dye. In the present study, the influence of methylene blue and methylene green on the effectiveness of pulmonary valve and aorta collagen modification was evaluated on the basis of photooxidized tissues sensitivity to pepsin digestion. The components...
The use of biological materials in construction of bioprostheses requires the application of different chemical or physical procedures of fixation increasing bioprostheses resistance to enzymatic or chemical degradation and reducing their antigenicity. Methods typically concentrate on creating additional intra- and intermolecular chemical bonds between collagen molecules. This review focuses on the...
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