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Progress in molecular biology, large number of known bacterial sequences and a number of microbiological genome sequencing projects finished or running allow to think about creating in vitro the DNA code in order to obtain new metabolites. Here, we describe the attempts of biosynthesis of new polyketides by designing new genes coding polyketide synthases. In assembling new polyketide synthases, the...
Many bacterial species use small chemical molecules as signaling factors. Signal molecules are released into the environment and once a threshold concentration level has been achieved, they trigger a response in the target cells. This system of cell-cell signaling, termed as ?quorum sensing?, plays an important role in the coordination of the growth and other processes in bacterial populations. Two...
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