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ObjectivesPegylated‐interferon/ribavirin dual therapy for hepatitis C virus (HCV) infection has a lower sustained virological response (SVR) rate in HIV/HCV‐coinfected patients than in HCV monoinfected patients, but little is known about the relative effectiveness of teleprevir‐based triple therapy in the two groups.
MethodsData on 33 coinfected and 116 monoinfected patients were analysed on an intention‐to‐treat...
Celem niniejszego artykułu jest krótki przegląd obecnie stosowanych metod oceny skuteczności i efektywności organizacji zorientowanych na ciągłe doskonalenie procesów i wyrobu. Ma on także na celu wskazanie metody lub grupy metod najbardziej przydatnej do oceny przedsiębiorstwa funkcjonującego w ramach formalnego systemu zarządzania jakością.
BackgroundAmongst Caucasian, Hispanic and African Americans with genotype 1 hepatitis C virus (HCV), there is a wide variation in response to treatment with peginterferon alfa‐2a (PEG‐IFN alfa‐2a) and ribavirin.
AimTo evaluate the pharmacokinetics (PK) of PEG‐IFN alfa‐2a and ribavirin among these three groups.
MethodsForty‐seven patients with genotype 1 CHC (17 African Americans, 14 Hispanics and...
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