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Abstract The nitric oxide (NO) donor sodium nitroprusside (SNP) applied to the round window membrane has recently been found to increase cochlear blood flow (CoBF) in normal guinea pigs and in normal and presbyacusic mice. This study examined the effect of topical applications of SNP on experimentally impaired CoBF in anesthetized guinea pigs. Small (3 l) portions of 3% SNP were applied to the round...
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