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HintergrundDer Transkriptionsfaktor HIF-1 („hypoxia-inducible factor-1“) reguliert unter Ischämie/Hypoxie die Expression von Genen für Glukoseversorgung, Wachstum, Stoffwechsel, Redoxreaktionen und Durchblutung. Im Hinblick auf Tinnitus und Schwerhörigkeit wurden HIF-1-Aktivität und Expression von HIF-1-abhängigen Genen in der Kochlea unter Ischämie/Hypoxie untersucht.Material/MethodenHIF-1 wurde...
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