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Exposure to nickel oxide nanoparticles (NiONPs), which have been widely produced and applied in industry, leads to adverse pulmonary and systemic effects. The aim of this study is to investigate the involvement of apoptosis and ferroptosis in NiONPs‐induced acute lung injury (ALI). Intratracheal instillation of NiONPs into mice elevated the levels of pro‐inflammatory cytokines, neutrophils, and proteins...