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Lumpectomy with microscopically clear margins is a safe and effective approach for surgical management of breast carcinoma. Margins are positive for tumor in 18–50% of lumpectomies, as it is not possible to accurately determine the shape or microscopic borders of a tumor preoperatively or intraoperatively. We examined the 3D microanatomy and growth patterns of common breast carcinoma subtypes to provide...
Microscopically clear lumpectomy margins are essential in breast conservation, as involved margins increase local recurrence. Currently, 18–50% of lumpectomies have close or positive margins that require re‐excision. We assessed the ability of micro‐computed tomography (micro‐CT) to evaluate lumpectomy shaved cavity margins (SCM) intraoperatively to determine if this technology could rapidly identify...
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