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The present studies were carried out in order to assess the protective effects of selenium against cadmium toxicity in pregnant hamsters. On the 8th day of gestation the females were dosed subcutaneously either with cadmium or with cadmium and selenium in the following doses (mg per kilogram of body weight): 0, 1 Cd, 1 Cd + 1 Se, 2 Cd, 2 Cd + 2 Se. In groups treated with cadmium decreased litter...
Three groups of 25 female rats each were dosed ad libitum with a sodium fluoride solution containing 0 mg F/dm³, 20 mg F/dm³, and 40 mg F/dm³ in the drinking water 3 to 5 weeks before pregnancy and 3 weeks after insemination. The doses used did not produce any teratogenic effect except for the highest dose (40 mg/dm³) producing foetus abnormalities in a few cases.
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