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Digital Spectral Analysis of DNA sequence using AR Models have long been proved to be superior to classical Fourier Transform techniques. Here authors have applied a special case of all-pole model using Prony's method to DNA sequence from various Chromosomes for Power Spectral Density (PSD) estimation in order to identify protein-coding regions. A quaternary mapping method comprising real and imaginary...
Gene prediction is an important topic in genomic research. Various techniques are in use for identification of protein coding regions in genes. Application of Fourier technique is one of the most popular methods of gene prediction, in which prediction algorithm is based on period-3 property of DNA where it exhibits a prominent peak in coding region. Spectrum estimation by Fourier method generates...
Accurate exon prediction in a genome is extremely important for understanding of life processes. Researchers use various techniques for detecting accurate location of exons. A digital filter model has been proposed in this paper for the prediction of exons in DNA sequence. The technique involves conversion of DNA character string into a numerical sequence using weak-strong bonding of nucleotides and...
The objective of this paper is to estimate the spectral content of coding and non-coding segments of DNA sequence by Parametric method. An attempt has been made so that by analyzing this estimated spectral content, the hidden internal properties of the DNA sequence can be brought into light in order to identify coding regions from non-coding ones. In this approach the DNA sequence from various Homo...
During the last several years, substantial progress has been made in developing high-throughput experimental techniques that produce large amounts of genomic data pertaining to molecular activities in cells. Consequently, a great deal of research is being focused on addressing important problems in molecular biology by analyzing these data using mathematical and computational approaches. Genomic signal...
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