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Imipramine belongs to a class of tricyclic antidepressants which augment monoaminergic transmission in a brain and are prevailingly used in treatment of depressive disorders. Increased availability of neurotransmitters (e.g., noradrenaline and serotonin) results among others, in modulation of the activity of G protein-coupled receptors and other proteins involved in intracellular signaling. The study...
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