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The in-line X-ray phase contrast imaging technique relies on the measurement of the Fresnel diffraction intensity patterns associated to a phase shift induced by the object. The simultaneous recovery of the phase and of the absorption is an ill-posed nonlinear inverse problem. If the object is made up of several homogeneous materials, the absorption and the phase are proportional in each material...
Phase retrieval from Fresnel diffraction patterns is a nonlinear ill-posed inverse problem of paramount importance in various areas of applied physics. Recently a new non-linear iterative algorithm based on a Landweber method with an analytic calculation of the Frechet derivative adjoint has been proposed. In this work, we refine this scheme by introducing Fienup projectors in the algorithm. The new...
Bone fragility involved in diseases such as osteoporosis implicates many mechanisms at the cellular level. It was recently shown that the lacunar-canalicular network interconnecting osteocytes has a major role in mechanosensitivity. So far, this system has only been studied from 2D microscopic images. In a previous work, we demonstrated the feasibility of synchrotron radiation micro-CT with a voxel...
A method for simultaneous 3D imaging and analysis of microvascularization and bone microstructure in rat bone is presented. The method is based on the use of quantitative synchrotron micro-computed tomography (SR-??CT) coupled to an automatic image analysis procedure. Previously, analysis of bone microvascularization has generally been performed from 2D histology. The proposed method enables for the...
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