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Purpose/Objective: Inverse planning is a required approach when dealing with the complexity of variables present in an intensity modulated plan. However, an inverse planning system is only as useful as it is 1) easy to use and 2) predictable in its result. This is especially the case when the target goals and structure limits specified by the user all cannot be achieved. We have previously developed...
PURPOSE: To gain experience in measuring quality of life (QOL) using the FACT-L in patients (pt) with non small cell lung cancer (NSCLC) treated with an altered fractionation regimen, HART, in a Phase II, multiinstitutional ECOG trial.MATERIALS AND METHODS: Version 2 of FACT-L, with 43 questions in 6 subscale categories (8 physical well-being, 8 social/family well-being, 3 relationship with doctor,...
Objectives: Based on preclinical studies demonstrating a direct correlation between duration of IUdR infusion and percent cells labeled as well as amount thymidine replaced by IUdR, we conducted a Phase I trial to: (1) investigate the maximum tolerated dose (MTD) and systemic toxicities of a continuous 28 day IUdR infusion; (2) analyze percent IUdR-thymidine replacement in peripheral granulocytes...
Purpose: To retrospectively evaluate outcome after first relapse for 79 patients with stage I (n=32) and II (n=47) follicular small cleaved-cell (FSC, n=48) and follicular mixed small cleaved-cell and large-cell (FMX, n=31) lymphoma treated with Radiation Therapy (RT) at Stanford University between 1961 and 1994.Patients and Methods: Most patients had received doses of 35 to 45 Gy to involved (n=30)...
PURPOSE: 1. What is the attrition rate , i.e. patients who do not initiate CHFRT? 2. To evaluate ≥ grade 3 (G 3) acute toxicities from CHFRT.MATERIALS AND METHODS: Children aged 3-21, with HRPNET received 5 courses of CT (vincristine, VP-16, cisplatinum & cytoxan alternating with carboplatin & VP-16) followed by CHFRT (1 Gy bid) to varying total doses, based on disease extent (maximum...
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