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The study aimed to assess the role of CD151-integrin α3β1 (INGA3) complex as a potential prognostic indicator in OSCC and to examine whether mapping of its expression in the invasive front separately from that in the rest of the tumour would have an impact on the predictive value of the results. CD151/INGA3 profiles were compared with that of EGFR.Protein distributions were analysed either in the...
WWOX is a tumour suppressor gene involved in various tumours including breast cancer. High chromosomal abnormalities in a genomic region spanned by WWOX are associated with the fact that this gene covers approximately 1 million base pairs of the second most affected among common chromosomal fragile sites FRA16D. We evaluated WWOX expression levels in breast cancer samples in association with diagnostics–prognostics...
As a part of a program aimed at discovering new therapeutically active compounds, platinum choline complex of formula (choline) 2 (PtCl 4 ) has been synthesized. Complex gave satisfactory elemental analyses and the purity was verified by IR and 1 H and 195 Pt NMR spectroscopy. The antineoplastic activity of platinum(II) choline complex was initially examined...
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