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Aims
To characterise the clinicopathological features of amyloidosis due to EGF‐containing fibulin‐like extracellular matrix protein 1 (EFEMP1), a newly described amyloid type.
Methods and results
We identified cases by searching the Mayo Clinic amyloid liquid chromatography and tandem mass spectrometry typing database for specimens with the universal amyloid signature proteins, abundant EFEMP1...
AimsPrognostication and treatment selection for cardiac amyloidosis requires accurate amyloid typing. The aim of this study was to investigate the utility of histomorphology for predicting type.
Methods and resultsAutopsy cases with cardiac amyloidosis (1998–2010) were typed by the use of mass spectrometry‐based proteomics. Deposition patterns were correlated with amyloid type. Among 108 decedents...
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