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Several topical products contain nanometric TiO 2 (nano-TiO 2 ), which is a useful and safe component that absorbs UV light and does not cross skin barrier. However, nano-TiO 2 may impregnate the first layer of the skin (stratum corneum, SC) and generate free radicals, even under low UV irradiation. These properties, largely dependent on TiO 2 surface chemistry, may...
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