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Objective
Islet microcirculation is mainly composed by IMECs. The aim of the study was to investigate the differences in gene expression profiles of IMECs upon glucose toxicity exposure and insulin treatment.
Methods
IMECs were treated with 5.6 mmol L−1 glucose, 35 mmol L−1 glucose, and 35 mmol L−1 glucose plus 10−8 mol L−1 insulin, respectively. Gene expression profiles were determined by microarray...
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