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Out of various subtypes of human immunodeficiency virus type 1 (HIV‐1), subtype B and C cause most of the infections worldwide. Clade specific differences have been reported in differences in clinical picture of HIV pathogenesis. Transcription of the HIV‐1 genome is regulated by the interaction of HIV Tat protein to the trans‐activation response (TAR) element. The differential binding of clade B and...
Background Japanese encephalitis virus (JEV) is the causative agent of Japanese encephalitis which is more prevalent in South and Southeast Asia. JEV is a neurotropic virus which infiltrates into the brain through vascular endothelial cells. JEV infects neurons and microglial cells which causes neuronal damage and inflammation. However, JEV also evades the cellular immune response to survive in...
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