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Biliary atresia (BA) is a neonatal liver disease featuring cholestasis and severe liver fibrosis (LF). Despite advances in the development of surgical treatment, lacking an early diagnostic marker and intervention of LF invariably leads to death from end‐stage liver disease in the early years of life. We previously reported that knockout of sphingosine 1‐phosphate receptor 2 (S1PR2) protected mice...
Fulminant hepatic failure (FHF) is a clinical syndrome characterized by sudden and severe impairment of liver function. Mesenchymal stem cells (MSCs) have been proposed as a promising therapeutic approach for FHF. In this study we used Propionibacterium acnes (P. acnes)‐primed, lipopolysaccharide (LPS)‐induced liver injury in mice as an animal model of human FHF. We demonstrated that administration...
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