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T‐box gene Tbx4 is critical for the formation of the umbilicus and the initiation of the hindlimb. Previous studies show broad expression in the allantois, hindlimb, lung and proctodeum. We have examined the expression of Tbx4 in detail and used a Tbx4‐Cre line to trace the fates of Tbx4‐expressing cells. Tbx4 expression and lineage reveal that various distinct appendages, such as the allantois, hindlimb,...
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