Search results for: Gema Rodríguez

Items from 1 to 20 out of 32 results

article

Combination of HPLC with organic and inorganic mass spectrometry to study the metabolic response of the clam Scrobicularia plana to arsenic exposure

Gema Rodríguez‐Moro, Tamara García‐Barrera, Chiara Trombini, Julián Blasco, more

Arsenic is a toxic element extensively studied in the marine environment due to differential toxicological effects of inorganic and organic species. In the present work, the bivalve Scrobicularia plana was exposed to As^V (10 and 100 μg/L) for 14 days to evaluate the metabolic perturbations caused by this element. Arsenic speciation and metabolomic analysis were performed in the digestive gland of...

article

Back Cover: Combination of HPLC with organic and inorganicmass spectrometry to study the metabolic response of the clam Scrobicularia plana to arsenic exposure

Gema Rodríguez‐Moro, Tamara García‐Barrera, Chiara Trombini, Julián Blasco, more

ELECTROPHORESIS > 39 > 4 > NA - NA

DOI: 10.1002/elps.201700318 The cover picture shows the toxicity of arsenic in the marine environment in relation to the chemical form of this element. Scrobicularia plana reflects the biological response to inorganic arsenic, using elemental and molecular mass spectrometry, which reveals the greater presence of non‐toxic arsenobetaine besides significant concentrations of less toxic methylated and...

article

Preliminary experience on the safety and tolerability of mechanical “insufflation-exsufflation” in subjects with artificial airway

Miguel Sánchez-García, Passio Santos, Gema Rodríguez-Trigo, Fernando Martínez-Sagasti, more

Intensive Care Medicine Experimental > 2018 > 6 > 1 > 1-9

Background Catheter suctioning of respiratory secretions in intubated subjects is limited to the proximal airway and associated with traumatic lesions to the mucosa and poor tolerance. “Mechanical insufflation-exsufflation” exerts positive pressure, followed by an abrupt drop to negative pressure. Potential advantages of this technique are aspiration of distal airway secretions, avoiding trauma, and...

article

Spatial Shifts in Soil Microbial Activity and Degradation of Pasture Cover Caused by Prolonged Exposure to Cement Dust

Fuensanta Caravaca, Zenaida Lozano, Gema Rodríguez‐Caballero, Antonio Roldán

Land Degradation & Development > 28 > 4 > 1329 - 1335

We ascertained the relationship between the zonal pattern and the pasture vegetation of a volcanic soil polluted with dust from a cement factory after 70 years of operation, with parameters linked to soil microbial activity (soil basal respiration and hydrolases) and physical–chemical properties. Six sampling zones were established at distances of 1, 2, 3, 4, 5 and 6 km away from the cement plant,...

chapter

How Much Time Did It Take to Notify a Bug? Two Case Studies: ElasticSearch and Nova

Gema Rodriguez Perez, Gregorio Robles, Jesus M. Gonzalez Barahona

2017 IEEE/ACM 8th Workshop on Emerging Trends in Software Metrics (WETSoM) > 29 - 35

2017 IEEE/ACM 8th Workshop on Emerging Trends in Software Metrics (WETSoM)

The Time To Notify (TTN) a bug is a valuable metricin the software maintenance and evolution studies that describeshow much time it takes for a bug to be notified/reported in theissue tracking system since the time the bug was introduced intothe source code. Even so, it is still a challenge to exactly calculateit since no precise way exists to locate where and when the bugoriginated. This paper aims...

article

Glutathione Increases in Response to a Glucose Challenge in Diabetic Rat Hearts

Max Thorwald, Gema Rodriguez, Marco Antonio Rodriguez, Daisuke Nakano, more

Free Radical Biology and Medicine > 2016 > 100 > S > S112

Diabetic hearts are in great risk of increased oxidant production from sustained elevations of glucose through activation of several pathways. One of the major sources of oxidant production within the cell are mitochondria through substrate metabolism. Oxidation of mitochondrial enzymes may impair their function resulting in accumulation of intermediates and reverse electron transfer, which contributes...

chapter

Time Evolution of Deformation Using Time Series of Differential Interferograms: Application to La Palma Island (Canary Islands)

Patricia A. Perlock, Pablo J. González, Kristy F. Tiampo, Gema Rodríguez-Velasco, more

Pageoph Topical Volumes > Earth Sciences and Mathematics > 1531-1554

Differential interferometry is a very powerful tool for detecting changes in the Earth’s crust where coherence conditions are good, but is difficult to employ in some volcanic areas due to dense vegetation. We apply two differential InSAR methods using the time series associated with the interferograms to perform a phase analysis on a data set for La Palma island (Canary Islands) from the ERS-1 and...

article

Bioactive bilayered dressing for compromised epidermal tissue regeneration with sequential activity of complementary agents

Felisa Reyes-Ortega, Alberto Cifuentes, Gema Rodríguez, María Rosa Aguilar, more

Acta Biomaterialia > 2015 > 23 > C > 103-115

The article deals with the design, preparation, and evaluation of a new bilayered dressing for application in the healing of compromised wounds. The system is based on the sequential release of two complementary bioactive components to enhance the activation of the regeneration of dermal tissue. The internal layer is a highly hydrophilic and biodegradable film of gelatin and hyaluronic acid (HG),...

article

Pulmonary rehabilitation

María Rosa Güell Rous, Salvador Díaz Lobato, Gema Rodríguez Trigo, Fátima Morante Vélez, more

Archivos de Bronconeumologia (English Edition) > 2014 > 50 > 8 > 332-344

Pulmonary rehabilitation (PR) has been shown to improve dyspnea, exercise capacity and health-related quality of life in patients with chronic obstructive pulmonary disease (COPD). PR has also shown benefits in diseases other than COPD but the level of evidence is lower. The fundamental components of PR programs are muscle training, education and chest physiotherapy. Occupational therapy, psychosocial...

article

Vibration response imaging versus perfusion scan in lung cancer surgery evaluation

Nuria Marina, Gema Rodriguez-Trigo, Unai Jimenez, Beatriz Morales, more

The Journal of Thoracic and Cardiovascular Surgery > 2014 > 147 > 2 > 816-821

Ventilation/perfusion scan is a standard procedure in high-risk surgical patients to predict pulmonary function after surgery. Vibration response imaging is a technique that could be used in these patients. The objective of our study was to compare this imaging technique with the usual scanning technique for predicting postoperative forced expiratory volume.We assessed 48 patients with lung cancer...

article

Evaluation of the persistence of functional and biological respiratory health effects in clean-up workers 6years after the Prestige oil spill

Jan-Paul Zock, Gema Rodríguez-Trigo, Emma Rodríguez-Rodríguez, Ana Souto-Alonso, more

Environment International > 2014 > 62 > Complete > 72-77

Fishermen who had participated in clean-up activities of the Prestige oil spill showed increased bronchial responsiveness and higher levels of respiratory biomarkers 2years later. We aimed to evaluate the persistence of these functional and biological respiratory health effects 6years after clean-up work. In 2008/2009 a follow-up study was done in 230 never-smoking fishermen who had been exposed to...

article

Study of the chelating properties of Ge(OH)₂ functionality as metal binding group for Zn²⁺ cation in simplified protease-like environments: a DFT analysis

Pilar Gema Rodríguez Ortega, Manuel Montejo, Juan Jesús López González

Journal of Molecular Modeling > 2014 > 20 > 9 > 1-11

The development of protease’s inhibitors is an active field of research in the pharmaceutical industry. As concerns the design of new inhibitors, the theoretical study of the binding patterns and energies of known metal binding groups (MBGs) toward Zn ²⁺ using quantum-chemical calculations may offer a better understanding of their interaction models and may be useful for the improvement and design...

article

Thermosensitive Macroporous Cryogels Functionalized With Bioactive Chitosan/Bemiparin Nanoparticles

Hazel Peniche, Felisa Reyes‐Ortega, María R. Aguilar, Gema Rodríguez, more

Macromolecular Bioscience > 13 > 11 > 1556 - 1567

Thermosensitive macroporous scaffolds of poly(N‐isopropylacrylamide) (polyNIPA) loaded with chitosan/bemiparin nanoparticles are prepared by the free radical polymerization in cryogenic conditions. Chitosan/bemiparin nanoparticles of 102 ± 6.5 nm diameter are prepared by complex coacervation and loaded into polyNIPA cryogels. SEM image reveal the highly porous structure of cryogels and the integration...

article

Stabilizing factors of the molecular structure in silicon-based peptidomimetics in gas-phase and water solution. Assessment of the correlation between different descriptors of hydrogen bond strength

María Pilar Gema Rodríguez Ortega, Manuel Montejo, Juan Jesús López González

Journal of Molecular Modeling > 2013 > 19 > 10 > 4293-4304

The use of DFT (B3LYP and M06L) and ab initio (MP2) computational methods allowed us to perform a thorough conformational study of N-[dihydroxy (methyl)silyl]methylformamide (DHSF) and 3-[dihydroxy (methyl) silyl] propanamide (DHSP), that could be considered simplified models of the environment of the silanediol group in silicon gem-diols that have proven efficiency as protease inhibitors. We have...

article

Quantum chemical study of silanediols as metal binding groups for metalloprotease inhibitors

Igor S. Ignatyev, Manuel Montejo, Pilar Gema Rodríguez Ortega, Juan Jesús López González

Journal of Molecular Modeling > 2013 > 19 > 4 > 1819-1834

DFT (B3LYP and M06L) as well as ab initio (MP2) methods with Dunning cc-pVnZ (n = 2,3) basis sets are employed for the study of the binding ability of the new class of protease inhibitors, i.e., silanediols, in comparison to the well-known and well-studied class of inhibitors with hydroxamic functionality (HAM). Active sites of metalloproteases are modeled by [R₃M-OH₂]²⁺ complexes, where R stands...

article

Standards for Quality Care in Respiratory Rehabilitation in Patients With Chronic Pulmonary Disease

Maria Rosa Güell, Pilar Cejudo, Gema Rodríguez-Trigo, Juan Bautista Gàldiz, more

Archivos de Bronconeumologia (English Edition) > 2012 > 48 > 11 > 396-404

Respiratory rehabilitation (RR) has been shown to be effective with a high level of evidence in terms of improving symptoms, exertion capacity, and health-related quality of life (HRQL) in patients with COPD and in some patients with diseases other than COPD. According to international guidelines, RR is basically indicated in all patients with chronic respiratory symptoms, and the type of program...

article

Basketball Players' Perception of Their Coaches

Antonio Antón, Gema Rodríguez

Human Movement > 2011 > 12 > 4 > 347-377

<bold>Purpose.</bold> The aim of this study was to analyse Spanish women basketball players' perception of their coaches in order to discover whether this perception is different from those in other sports and which character traits are the most appreciated in the sport of basketball. <bold>Methods.</bold> We administered a questionnaire survey in December 2010 to a total of...

article

Basketball Players' Perception of Their Coaches

Antonio Antón, Gema Rodríguez

Human Movement > 2011 > 12 > 4 > 347-377

article

Lactate-mediated enzymatic reduction of metmyoglobin in vitro

Gema Rodríguez, Yuan H. Brad Kim, Sophie Faget, Christelle Rosazza, more

Food Chemistry > 2011 > 125 > 2 > 732-735

This study examined the lactate-mediated enzymatic reduction of equine metmyoglobin (MMb) by using various lactate salts (sodium, potassium and calcium) and bovine m. triceps brachi extracts in vitro. The equine MMb was reduced by the assay mixture containing lactate, NAD ⁺ , and the muscle extract at pH 5.7. In the absence of the bovine muscle extract, NAD ⁺ or l-lactate in the assay...

article

Impact of Preventive Treatment With Long-Acting β2-Adrenergic Agonists and Inhaled Corticosteroids on the Morbidity and Mortality of Severe Asthma Exacerbations in 1543 Patients

Vicente Plaza, Jesús Bellido-Casado, Gustavo J. Rodrigo, Javier Solarte, more

Archivos de Bronconeumologia (English Edition) > 2009 > 45 > 11 > 545-549

Recent systematic reviews and meta-analyses examining long-acting β ₂ -adrenergic agonists (LABA) as maintenance treatment for asthma have shown surprisingly conflicting results. The aim of the present study was to determine the impact, in terms of efficacy and safety, of previous maintenance treatment on severe asthma exacerbations.We retrospectively evaluated the clinical characteristics...

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INFONA - science communication portal

Search results for: Gema Rodríguez

Combination of HPLC with organic and inorganic mass spectrometry to study the metabolic response of the clam Scrobicularia plana to arsenic exposure

Back Cover: Combination of HPLC with organic and inorganicmass spectrometry to study the metabolic response of the clam Scrobicularia plana to arsenic exposure

Preliminary experience on the safety and tolerability of mechanical “insufflation-exsufflation” in subjects with artificial airway

Spatial Shifts in Soil Microbial Activity and Degradation of Pasture Cover Caused by Prolonged Exposure to Cement Dust

How Much Time Did It Take to Notify a Bug? Two Case Studies: ElasticSearch and Nova

Glutathione Increases in Response to a Glucose Challenge in Diabetic Rat Hearts

Time Evolution of Deformation Using Time Series of Differential Interferograms: Application to La Palma Island (Canary Islands)

Bioactive bilayered dressing for compromised epidermal tissue regeneration with sequential activity of complementary agents

Pulmonary rehabilitation

Vibration response imaging versus perfusion scan in lung cancer surgery evaluation

Evaluation of the persistence of functional and biological respiratory health effects in clean-up workers 6years after the Prestige oil spill

Study of the chelating properties of Ge(OH)₂ functionality as metal binding group for Zn²⁺ cation in simplified protease-like environments: a DFT analysis

Thermosensitive Macroporous Cryogels Functionalized With Bioactive Chitosan/Bemiparin Nanoparticles

Stabilizing factors of the molecular structure in silicon-based peptidomimetics in gas-phase and water solution. Assessment of the correlation between different descriptors of hydrogen bond strength

Quantum chemical study of silanediols as metal binding groups for metalloprotease inhibitors

Standards for Quality Care in Respiratory Rehabilitation in Patients With Chronic Pulmonary Disease

Basketball Players' Perception of Their Coaches

Basketball Players' Perception of Their Coaches

Lactate-mediated enzymatic reduction of metmyoglobin in vitro

Impact of Preventive Treatment With Long-Acting β2-Adrenergic Agonists and Inhaled Corticosteroids on the Morbidity and Mortality of Severe Asthma Exacerbations in 1543 Patients

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