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The in vitro antitumor activity of novel combretastatin-like 1,5- and 1,2-diaryl-1H-imidazoles was evaluated against the NCI 60 human tumor cell lines panel. Compounds 2d and 2g proved to be more cytotoxic than CA-4 in tests involving their evaluation over a 10 −4 –10 −8 range. Docking experiments showed a good correlation between the MG_MID Log GI 50 values of all these compounds...
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