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Protein-polymer hybrids can act as giant monolayer-forming amphiphiles at the air-water interface. Using biotinylated polystyrene (PSb) as the hydrophobic part and streptavidin (SAv) as a hydrophilic end of the giant amphiphile, monolayer formation and subsequent deposition leads to a well defined solid-supported monolayer, in which the remaining free sites of the polymer-bound SAv are accessible...
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