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Nanoarray Systems
In article number 2306168, Claudia Corbo and co‐workers exploited a protein corona‐based nanoarray system composed of six diverse nanoparticles for its capability of detecting coronary artery disease. The disease‐specific protein coronas are used to identify crucial proteins for detection and create classification algorithms. It is demonstrated that this approach could be an innovative,...
Coronary artery disease (CAD) is the most common type of heart disease and represents the leading cause of death in both men and women worldwide. Early detection of CAD is crucial for decreasing mortality, prolonging survival, and improving patient quality of life. Herein, a non‐invasive is described, nanoparticle‐based diagnostic technology which takes advantages of proteomic changes in the nano‐bio...
Nanozyme
Nanoparticle surface structures can mediate enzyme‐mimetic activities and expedite biological interactions with cell membrane via engineered protein corona formation. Reducible metal oxide nanoparticles can allow tunable, therapeutic redox reactions such as the generation or scavenging of radicals. More details can be found in article number 2211261 by Sudipta Seal and co‐workers.
Reducible metal oxide nanozymes (rNZs) are a subject of intense recent interest due to their catalytic nature, ease of synthesis, and complex surface character. Such materials contain surface sites which facilitate enzyme‐mimetic reactions via substrate coordination and redox cycling. Further, these surface reactive sites are shown to be highly sensitive to stresses within the nanomaterial lattice,...