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Radiopharmacological investigations of [18F]NS14490 have proven that this radiotracer could be a potential PET radiotracer for imaging of alpha7 nicotinic acetylcholine receptor particularly with regard to vulnerable plaques of diseased vessels. For further optimisation of the previously automated one-pot radiosynthesis of [18F]NS14490 using a tosylate precursor, precursors with other leaving groups...
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