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Background CD73 is one of the critical component in the formation of immunosuppressive microenvironment in cancers. We aimed to provide an overview of the current status of CD73 expression and its relationship with clinicopathlogical features and prognosis in different cancers. Methods PubMed, Web of Science, EMBASE and Cochrane library were searched to identify the relevant studies. CD73 expression...
Although maintenance therapy has been a routine treatment paradigm for advanced non-small cell lung cancer (NSCLC), there is currently lack of direct evidence to identify patients most likely to benefit from maintenance therapy for advanced NSCLC.Trials comparing maintenance therapy with placebo or observation in NSCLC were identified. The primary endpoint was overall survival (OS) in trial population...
In the past decade, a number of case–control studies have been carried out to investigate the relationship between ABCA1 polymorphisms and Alzheimer's disease (AD). However, these studies have yielded contradictory results. To investigate this inconsistency, a meta-analysis was performed.Databases including PubMed, Web of Science, EMBASE and CNKI were searched to find relevant studies. Odds ratios...
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