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To investigate the efficacy and safety of low-concentration 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in the treatment of different severity of acne vulgaris and optimize the treatment regimen.A self-controlled multicenter clinical trial was carried out in 15 centers throughout China. A total of 397 acne patients of grade II–IV received 3- or 4-session PDT treatment. 5% ALA gel was applied...
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