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To determine the molecular mechanisms of hypertonic saline on nasal disorders.Primary human nasal epithelial cells (HNECs) were treated with 0.9 and 3% saline for 12h. CLC-3 was detected in HNECs by immunohistochemistry, reverse transcriptase-polymerase chain reaction (RT-PCR) and western blotting.Positive expression of CLC-3 was detected in HNECs in all subjects by immunohistochemistry. The relative...
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