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The antagonism of LINGO‐1, a CNS‐specific negative regulator of neuronal survival, was shown to promote short‐term survival of retinal ganglion cell (RGC) in an ocular hypertension model. LINGO‐1 antagonists, combined with brain‐derived neurotrophic factor (BDNF), can increase the length of neuron survival through an unclear molecular mechanism. To determine the relationship between LINGO‐1 and BDNF/TrkB...
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