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The properties of diflunisal, a widely used analgesic, were studied in physiologic solutions, 0.15 mol·dm−3 NaCl. Solubility and protonation constants were determined and its behavior as ligand towards Ca(II) and Mg(II) was investigated. Solubility and protonation constants of diflunisal at 25 °C and 0.15 mol·dm−3 were obtained from electromotive force measurements of galvanic cells using coulometric...
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